预测试验成功的预测因素,没有导管的试验,对于有尿路保留的男性
Masato Takanashi1, Hiroki Ito1,2, Takeshi Fukazawa2
1Department of Urology, Yokosuka Kyosai Hospital, Yokosuka, Japan.
Lower urinary tract symptoms
|June 6, 2023
概括
这项研究发现,药物状况会影响在男性急性尿路滞留患者中试验无导管自发排尿 (TWOC) 的成功. 根据患者是否接受药物,年龄和表现状况预测TWOC结果的不同.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 男人下尿道症状 男人下尿道症状
- 急性尿液保留症是什么意思
背景情况:
- 急性尿 (AUR) 需要干预,通常涉及无导管自发排尿 (TWOC) 的试验.
- 成功TWOC的预测因素以及先前存在的药物在AUR管理中的作用仍然不完全理解.
研究的目的:
- 为了研究男性有AUR的TWOC结局.
- 为了确定成功TWOC的预测因素.
- 评估补充药物治疗对TWOC成功的影响.
主要方法:
- 对576名患有AUR和空气后残留量 (PVR) >250毫升的男性进行了回顾性研究,接受了TWOC.
- 患者分为药物治疗 (接受α1阻断剂) 和原始组.
- 通过PVR ≤150mL和无不适的排泄能力来定义TWOC的成功;如果失败,则表示重新插入.
主要成果:
- 原始组有更多的老年患者具有更高的性能状态 (PS) 和较小的前列腺体积.
- 药物治疗患者的年龄<80岁 (OR 1.701) 和原始患者的PS<2 (OR 2.710) 是TWOC成功的独立预测因素.
- 在各自组中,在成功和不成功的TWOC结果之间观察到显著的年龄和PS差异.
结论:
- 这是第一个根据药物状态对AUR患者进行分类的研究,揭示了不同的背景和TWOC预测因子.
- 药物状态影响患者特征和TWOC结果预测指标,这表明AUR的不同病因.
- 建议根据先前存在的药物状况为男性下尿路症状量身定制AUR管理.
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