对患有深感染的老年成人患者的评估:一项回顾性研究
Fu-Yuan Hsiao1, Chia-Ying Ho1,2, Kai-Chieh Chan1,3
1School of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ear, nose, & throat journal
|June 6, 2023
概括
患有深部感染 (DNI) 的老年患者经历了更严重的疾病,需要更多的干预措施,如输管和切口/排水. 迅速治疗对于这种脆弱人群的更好的结果至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 老年病的医生 老年病的医生
背景情况:
- 深部感染 (DNI) 是一种严重的疾病,特别是在成年人中,对老年人的结果的数据有限.
- 老年人通常免疫力低下,可能导致不同的DNI预后.
- 这项研究解决了对老年人与成年人群的DNI特征和结果的理解差距.
研究的目的:
- 为了比较老年患者 (65岁以上) 与成年患者 (18-65岁) 的深部感染 (DNI) 的临床特征,治疗和结果.
- 在老年人群中确定与DNI严重程度相关的风险因素.
- 为老年人深部感染的临床管理策略提供信息.
主要方法:
- 一项回顾性研究分析了2016年11月至2022年11月期间入院的398名深感染 (DNI) 患者.
- 对113名老年DNI患者和成人DNI患者的临床变量进行比较.
- 统计分析以确定住院,炎症标志物,并发病,干预和病原体分布的差异.
主要成果:
- 与成人患者相比,老年DNI患者的住院时间更长,C反应蛋白和血糖水平升高,糖尿病患病率更高.
- 较高的血糖水平被确定为老年人严重DNI的独立风险因素.
- 老年患者需要更高的呼吸道输管率和外科切割和排水 (I&D),尽管病原体分布在年龄组之间没有显著差异.
结论:
- 深部感染 (DNI) 在老年患者中呈现出更严重的临床过程和较差的预后,与成年人相比.
- 老年DNI患者需要更频繁的气道管理和手术干预.
- 尽管严重程度和治疗方法有差异,但深部感染的致病原体在老年人和成年人群中并没有显著差异,这强调了对老年人的及时和积极治疗的需要.
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