在多次治疗的玻璃眼患者中,激光形术的长期随访
Erika Rasmuson1, Boel Bengtsson2, Christina Lindén1
1Department of Clinical Sciences, Ophthalmology, Umeå University, Umeå, Sweden.
Acta ophthalmologica
|June 6, 2023
概括
激光膜整形 (LTP) 有效降低眼内压力 (IOP) 长期在前治疗 IOP ≥15 mmHg. 然而,LTP在治疗前IOP较低的患者中表现出有限的成功.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 手术干预 手术干预
背景情况:
- 开角青光眼的管理往往涉及多重治疗策略.
- 激光膜整形 (LTP) 是一种潜在的干预措施,用于降低眼内压力 (IOP).
- 对于已经服用多种IOP降低药物的患者,LTP的长期疗效需要评估.
研究的目的:
- 为了评估激光形术 (LTP) 在玻璃眼密集治疗研究 (GITS) 中的持续效果.
- 为了评估LTP在被随机选择为开角玻璃眼多重治疗方案的患者的疗效.
主要方法:
- 患有新诊断的未经治疗的开角青光瘤的患者接受了三种IOP降压药物一周.
- 在医疗治疗后,进行了360°或选择性激光轨道造形术 (LTP).
- 眼内压力 (IOP) 在LTP前被测量,并在60个月内反复测量.
主要成果:
- 在LTP前IOP≥15mmHg的眼睛中,在手术后48个月内观察到显著的IOP降低.
- 在LTP前IOP<15 mmHg的眼睛中没有发现显著的IOP降低.
- 只有不到13%的眼睛初始IOP≥15mmHg需要在48个月后增加治疗.
结论:
- 激光轨道造形术 (LTP) 可以在多次治疗的玻璃眼患者中提供持续的内血压降低,当基线内血压≥15 mmHg时.
- 在激光前眼内压低于15mmHg的患者中,LTP的成功率显著下降.
- 对于接受多种药物治疗的某些青光眼患者来说,LTP可能是一个有价值的长期治疗选择.
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