抵抗运动训练增加了对有氧高强度间歇训练的免疫调节适应能力
Nakisa Soltani1, Sayyed Mohammad Marandi1, Volga Hovsepian1
1Department of Exercise Physiology, Faculty of Sport Sciences, University of Isfahan, Isfahan, Iran.
European journal of sport science
|June 6, 2023
概括
在超重女性中,高强度间歇训练 (HIIT) 与抵抗运动 (HIIT/RE) 相结合,比有氧HIIT (HIIT/AE) 更有效地减少炎症. HIIT/RE显著降低关键炎症途径基因和血清标记物的调节,这表明对心脏代谢健康有好处.
科学领域:
- 运动生理学 运动生理学
- 免疫学 免疫学 免疫学
- 代谢健康 代谢健康
背景情况:
- 肥胖与慢性低度元炎症有关,部分由托尔类受体4 (TLR4) 途径介导.
- 高强度间歇训练 (HIIT) 已经显示出缓解炎症的潜力,但不同HIIT模式的比较有效性尚不清楚.
- 了解有氧对抗性HIIT对炎症路径的影响对于优化超重和肥胖个体的运动干预至关重要.
研究的目的:
- 为了比较有氧HIIT (HIIT/AE) 与 HIIT (HIIT/RE) 阻力运动在TLR4通路活性和超重和肥胖的年轻女性的元炎症的有效性.
- 研究这些HIIT协议对关键炎症标记物的影响,包括TLR4通路组件的基因表达和血清细胞因子水平.
主要方法:
- 一项为期10周的随机试验,涉及30名超重/肥胖的年轻女性.
- 参与者被分配到HIIT/AE (有氧自行车运动) 或HIIT/RE (联合阻力运动和自行车运动) 中,进行28分钟的会议.
- 测量包括TLR4通路元素 (TLR4,TRIF,MYD88,NF-κB,IRF3,TNFAIP3) 的基因表达和TNFα,IFNγ,IL-10和皮菌素的血清水平.
主要成果:
- 与HIIT/AE相比,HIIT/RE显著降低了TLR4,TRIF和IRF3基因表达的调节 (p <0.05).
- 与HIIT/AE相比,在HIIT/RE后,TNFα和IFNγ的血清水平显著降低 (p <0.05).
- 两组之间没有观察到阿迪波内克丁和IL-10水平的显著差异; TNFAIP3表达是可比的.
结论:
- 与HIIT (HIIT/RE) 结合抗力运动,在超重和肥胖女性中,与有氧HIIT (HIIT/AE) 相比,显示出优异的免疫调节效果.
- HIIT/RE有效地减少TLR4通路的关键组成部分,特别是TRIF依赖级联和相关的促炎细胞因子.
- 抵抗运动成分增加了HIIT的抗炎性适应,支持其对心脏代谢疾病风险较高的个体的处方.
更多相关视频
相关概念视频
Exercise and Muscle Performance
1.5K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.5K
Exercise and Cardiovascular Response
874
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
874
Exercise and Cardiac Output
1.1K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
1.1K
Cell-mediated Immune Responses
69.2K
Overview
69.2K
Tumor Immunotherapy
575
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
575
Development of Immunocompetence
366
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
366


