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类固醇的成本效益,延长了手术无需的间隔,在小囊狭窄
Jake A Langlie1, Luke J Pasick1, David E Rosow1
1Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA.
The Laryngoscope
|June 6, 2023
概括
连续内伤类固醇注射 (SILSI) 提供了一种成本效益 (CE) 的方法,以延长 subglottic 狭窄症 (SGS) 患者的无手术间隔 (SFI). 这种方法减少了重复内镜扩张 (ED) 的需要,节省了大量的成本.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 医学经济学 医学经济学
- 再生医学是一种再生医学.
背景情况:
- 重复内镜扩张 (ED) 对于下狭窄症 (SGS) 具有重大经济负担.
- 在SGS患者中,连续内溶性类固醇注射 (SILSI) 延长无手术间隔 (SFI) 的成本效益尚未得到充分确立.
研究的目的:
- 评估辅助性串联内伤性类固醇注射 (SILSI) 的成本效益 (CE) 在延长无手术间隔 (SFI) 患者的 subglottic狭窄症 (SGS).
- 为了确定SILSI是否是一个经济可行的替代方案来重复内镜扩张 (ED) 管理SGS.
主要方法:
- 进行了平衡分析,将SILSI的成本与重复ED进行比较.
- 关于SFI,干预成本和SILSI对SFI的影响的数据是从Luke等人进行的系统审查中收集的.
- SGS的病因包括异常,阳性或自身免疫.
主要成果:
- 与单独ED相比,SILSI将SFI延长了平均219.3天.
- 74.5%的SILSI处理的病例不需要进一步的ED.
- 如果SILSI (4剂量系列,约7,564.00美元) 在需要ED (约39,429.00美元) 的SGS复发中实现至少19.18%的绝对风险降低,那么它是具有成本效益的.
- 在预防重复性ED方面,SILSI显示了大约75%的ARR.
结论:
- 连续内伤性类固醇注射 (SILSI) 在经济上是合理的,用于治疗小结肠狭窄症 (SGS).
- 在延长外科内镜扩张 (ED) 间隔方面,SILSI证明具有成本效益.
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