Pso-Reg:一个现实生活中的牛皮的网络注册表
Emanuele Trovato1, Alessandra Cartocci2,3, Laura Calabrese1,4
1Unit of Dermatology, Department of Medical, Surgical and Neurological Science, University of Siena, Siena, Italy.
Italian journal of dermatology and venereology
|June 6, 2023
概括
牛皮病登记 (Pso-Reg) 收集了来自768名意大利牛皮病患者的现实数据. 结果突出了常见的并发症和当前的治疗模式,有助于个性化牛皮管理策略.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 流行病学 流行病学
背景情况:
- 牛皮 (PsO) 是一种普遍存在的免疫媒介炎症疾病,影响全球数百万人.
- 目前的疗法显示患者的反应各不相同,这表明对个性化治疗的临床需求尚未得到满足.
- 牛皮病登记 (Pso-Reg) 成立,以收集意大利牛皮病患者的真实数据.
研究的目的:
- 设计和开发一个基于电子的注册表 (Pso-Reg) 来收集有关牛皮患者的现实生活数据.
- 分析来自意大利牛皮患者队列的社会人口统计,临床,实验室和治疗数据.
主要方法:
- 一个多中心,回顾性,观察性队列研究,利用研究电子数据捕获 (REDCap) 工具.
- 包括所有在五个意大利医疗中心被诊断患有牛皮的患者.
- 收集全面的患者数据,包括人口统计,临床特征,并发症和治疗方法.
主要成果:
- 这项研究分析了768名患者 (58.1%是男性,平均年龄为55.5岁).
- 常见的并发症包括牛皮关节炎 (26.8%),高血压 (25.3%) 和糖尿病 (10%).
- 生物疗法最常见 (61.3%),其次是常规疾病修饰性抗风湿药物 (cDMARDs) (12.0%).
结论:
- 来自Pso-Reg的现实数据为牛皮患者的特征和管理提供了宝贵的见解.
- 这些发现可以为 psoriasis 的个性化治疗策略的开发提供信息.
- 该注册表支持基于现实患者数据的更为量身定制的牛皮管理方法.
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