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乳腺扫描人工智能算法与临床风险模型对5年乳腺癌风险预测的比较:一项观察性研究
Vignesh A Arasu1, Laurel A Habel1, Ninah S Achacoso1
1From the Division of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA 94612 (V.A.A., L.A.H., N.S.A., L.H.K., V.X.L., C.M.L., C.L.); Department of Radiology, Kaiser Permanente Northern California, Vallejo Medical Center, Vallejo, Calif (V.A.A.); Kaiser Permanente Washington Health Research Institute, Seattle, Wash (D.S.M.B.); Department of Radiology, Southern California Permanente Medical Group, Orange County, Irvine, Calif (J.B.C.); Department of Surgery (L.J.E.), Department of Radiology and Biomedical Imaging (N.M.H.), and Department of Epidemiology and Biostatistics (M.M.G., J.K.), University of California-San Francisco, San Francisco, Calif; Department of Medical Imaging Technology and Informatics, Southern California Permanente Medical Group, Pasadena, Calif (D.A.L.); Department of Biostatistics, University of California-Davis, Davis, Calif (D.L.M.); The Technology Group, The Permanente Medical Group, Oakland, Calif (D.A.N.); KP Information Technology, Kaiser Foundation Health Plan Inc and Kaiser Foundation Hospitals, Oakland, Calif (A.P.); Department of Artificial Intelligence and Human Health and Nash Family Department of Neuroscience (L.S.) and Department of Population Health Science and Policy, Department of Genetics and Genomic Sciences (W.S.), Icahn School of Medicine at Mount Sinai, New York, NY; and Department of Radiology, Hawaii Permanente Medical Group, Moanalua Medical Center, Honolulu, Hawaii (H.C.Y.).
人工智能 (AI) 算法显示,与乳腺癌监测联盟 (BCSC) 风险模型相比,乳腺癌风险预测在5年内得到了改进. 将AI与BCSC相结合,进一步提高了乳腺癌风险评估的准确性.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 人工智能在医学中的应用
背景情况:
- 现有的乳腺癌风险模型具有适度的预测歧视.
- 准确的风险评估对于指导查和预防策略至关重要.
研究的目的:
- 为了比较乳腺癌人工智能 (AI) 算法与乳腺癌监测联盟 (BCSC) 风险模型的预测性能.
- 为了评估发生乳腺癌的5年风险预测准确度.
主要方法:
- 一个回顾性病例-队列研究分析了从妇女的数据与负面查乳房图.
- 五个AI算法和BCSC风险模型被用来预测5年乳腺癌风险.
- 用于性能比较,计算了接收器运行特征曲线 (AUC) 下的时间依赖面积.
主要成果:
- 人工智能算法在5年乳腺癌风险预测中显示出更高的时间依赖AUC (0.630.67) 比BCSC模型 (0.61).
- 结合AI和BCSC模型的AUC略有改善 (0.660.68).
结论:
- 乳腺扫描人工智能算法在预测负面查检查的5年乳腺癌风险方面优于BCSC风险模型.
- 将人工智能与现有临床模型集成,可以提高乳腺癌风险预测能力.
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