相关实验视频

Updated: Jun 29, 2026

Engineering and Evolution of Synthetic Adeno-Associated Virus AAV Gene Therapy Vectors via DNA Family Shuffling
21:55

Engineering and Evolution of Synthetic Adeno-Associated Virus AAV Gene Therapy Vectors via DNA Family Shuffling

Published on: April 2, 2012

28.6K

选一种有效的双腺关联病毒分裂细胞因子基编辑系统,用于C-to-T转换

Qianyi Liu1,2, Yuxi Chen1,2, Sihui Hu1,2

  • 1MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.

Human gene therapy
|June 6, 2023
PubMed
概括

通过双腺相关病毒 (AAV) 传递的新分裂细胞因子基编辑器 (CBE) 系统可以实现高效的基因编辑. 这种双AAV方法克服了在体内基因治疗应用中的AAV大小限制.

关键词:
腺相关的病毒.细胞酶基编辑器编辑器基因编辑 基因编辑视网膜色素表皮质是视网膜色素表皮质.在分成的意义上说.

更多相关视频

A Nonsequencing Approach for the Rapid Detection of RNA Editing08:50

A Nonsequencing Approach for the Rapid Detection of RNA Editing

Published on: April 21, 2022

2.6K
Isolation of Next-Generation Gene Therapy Vectors through Engineering, Barcoding, and Screening of Adeno-Associated Virus AAV Capsid Variants09:20

Isolation of Next-Generation Gene Therapy Vectors through Engineering, Barcoding, and Screening of Adeno-Associated Virus AAV Capsid Variants

Published on: October 18, 2022

4.6K

相关概念视频

RNA Editing02:23

RNA Editing

RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...