多光谱网络的功能组织中的发展差异
Nathan M Petro1,2, Giorgia Picci1,2,3, Christine M Embury1,2
1Institute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE, United States.
Cerebral cortex (New York, N.Y. : 1991)
|June 6, 2023
概括
青少年 (9-15岁) 的大脑连接随着年龄的增长而变得更加分离,特别是在三角波和α频段,通过磁脑电图 (MEG) 测量. 这种发育转变会影响边缘和认知网络.
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 脑部成像 脑部成像
背景情况:
- 休息状态大脑连接性评估对于理解功能性大脑组织的发育变化至关重要.
- 以前的研究,主要是使用fMRI,表明在开发过程中从本地处理转向分布式处理.
- 在这种情况下,使用磁大脑摄影 (MEG) 的多谱功能连接仍然不那么明显.
研究的目的:
- 在典型发育的年轻人中使用MEG在休息期间研究多谱功能连接的发育变化.
- 在不同频段的脑网络组织中与年龄相关的改变的特征.
主要方法:
- 在101名典型发育的青少年 (9-15岁) 中,在闭眼休息期间检查了自发皮质活动,使用MEG.
- 计算的多光谱MEG图像和估计的功能连接使用200个大脑区域之间的相连贯的虚构部分 (Schaefer皮质地图).
- 分析了三角波,三角波,α,β和马频段的连接性.
主要成果:
- 德尔塔和阿尔法连接矩阵显示,随着年龄的增长,社区结构的增加.
- 连接权重通常随着年龄的增长而降低,在三角波段和α波段.
- 带差异与边缘皮层区域有关;α带差异涉及注意力和认知网络.
结论:
- 大脑的功能组织在青春期的发育过程中变得更加分离,这与之前的研究一致.
- 大脑连接的发育变化在正规大脑网络中表现出光谱特异性.
- 基于MEG的多谱分析为大脑组织中的神经发育变化提供了宝贵的见解.
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