照明条件影响视神经OCT血管学参数在健康的受试者中与中性学生
Pieter Nelis1,2,3, A Nieweler4, V Brücher4
1Department of Ophthalmology, University of Muenster Medical Center, Albert-Schweitzer-Campus 1, Building D15, 48149, Muenster, Germany. nelispieter@gmail.com.
Scientific reports
|June 6, 2023
概括
暴露于光线显著影响光学连贯断层扫描血管学 (OCTA) 测量中性瞳孔的视神经头血管密度. 脑膜瞳孔改变了OCTA血管的密度,建议在使用这些滴滴时谨慎使用.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 视网膜成像 视网膜成像
背景情况:
- 光学连贯断层扫描血管造影 (OCTA) 测量可以受到环境因素的影响.
- 了解影响OCTA的因素对于准确的视网膜和视神经头部分析至关重要.
研究的目的:
- 为了研究暴露在光明和黑暗中对斑点和视神经头部血管密度的影响.
- 为了评估瞳孔状态 (中性与心水) 在不同的光照条件下如何影响OCTA测量.
主要方法:
- 使用了高速,高分辨率的光谱域OCT系统,并使用了分光谱振幅脱相关血管学算法.
- 检查了55名健康志愿者,评估了在黑暗适应和暴露于光线后的OCTA血管密度.
- 分析了黄斑和视神经头部区域,应用了邦费罗尼对统计学意义的校正.
主要成果:
- 在中性瞳孔中,与黑暗适应相比,暴露于光线显著增加了视神经头血管密度 (p=0.002).
- 对于中性或中水性瞳孔,在明暗条件之间没有发现黄斑血管密度的显著差异.
- 视神经头部和黄斑区域在黑暗中暴露后,在中性瞳孔和脑膜瞳孔之间观察到血管密度的显著差异.
结论:
- 光线条件是OCTA测量的一个潜在影响因素,特别是在视神经头部.
- 脑膜瞳孔扩张显著影响OCTA血管密度测量,需要在临床实践中仔细考虑.
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