相关实验视频
Updated: Jul 27, 2025
06:31
Identification and Dissection of Diverse Mouse Adipose Depots
Published on: July 11, 2019
41.1K
脂肪组织与功能参数有关
Katharina Mueller-Peltzer1, Ricarda von Krüchten2, Roberto Lorbeer3
1Department of Diagnostic and Interventional Radiology, Faculty of Medicine Freiburg, Medical Center, Universitätsklinikum Freiburg, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany. katharina.mueller-peltzer@uniklinik-freiburg.de.
Scientific reports
|June 6, 2023
概括
内脏脂肪组织 (VAT) 与功能降低有关,特别是在没有心脏脏疾病的个体中,较高的cystatin C水平和较低的估计膜过率 (e-GFRcys).
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
背景情况:
- 肥胖的特点是脂肪组织积累过多.
- 脂肪组织对脏功能的直接影响尚不清楚.
- 了解这种关系对于预防病至关重要.
研究的目的:
- 调查内脏脂肪组织 (VAT) 和皮下脂肪组织 (SAT) 与功能标志物之间的关联.
- 在没有心脏脏疾病的个体中,检查VAT和SAT与血清肌素,囊素C和估计的球过率 (e-GFR) 的关系.
主要方法:
- 一项基于人口的研究 (KORA-MRI) 涉及377名受试者.
- 全身3T-MRI用于定量增值税和SAT.
- 血清肌素和细胞素C测量,使用各种公式计算e-GFR (e-GFRcrea,e-GFRcys,e-GFRcc).
- 对风险因素进行调整的线性回归分析.
主要成果:
- 内脏脂肪组织 (VAT) 显示出与e-GFRcys的显著反向关联 (p < 0.001) 和与血清囊素C的积极关联 (p < 0.001).
- 在总脂肪组织 (TAT),SAT和血清肌素,尿液微专蛋白或e-GFRcrea之间没有发现显著的关联.
- 对于BMI> 30的个体,分层分析证实了结果.
结论:
- 内脏脂肪组织 (VAT) 直接参与改变的cystatin C代谢.
- 增加的增值税与功能下降有关,根据基于cystatin C的e-GFR.
- 这些发现强调了内脏脂肪积累对脏健康的有害作用.
相关概念视频
01:21External Anatomy of the Kidney
1.2K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
1.2K
01:02Hypodermis
4.7K
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
4.7K
01:12Internal Anatomy of the Kidney
2.4K
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
2.4K