在薄截面胸部CT成像上对COVID-19肺炎原始SARS-CoV-2菌株和欧米克朗变体进行比较
Zeng Pingping1, Zhou Yanyu1, Sun Xuri1
1Department ICU of the Second Affiliated Hospital, Fujian Medical University, No. 34, Zhongshan North Road, Licheng District, Quanzhou City, Fujian, China.
Radiologie (Heidelberg, Germany)
|June 6, 2023
概括
计算机断层扫描 (CT) 扫描显示了Omicron-variant与原始株SARS-CoV-2肺炎的不同模式. 欧米克伦肺炎显示出更多的巩固和肺溢出,而原始菌株肺炎呈现出地面玻璃不透明度和肺下病变.
科学领域:
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 区分不同的SARS-CoV-2变种对于临床管理至关重要.
- 计算机断层扫描 (CT) 是诊断和评估COVID-19肺炎的关键成像方式.
- 之前的研究已经对原始菌株SARS-CoV-2的CT发现进行了描述,但关于Omicron变异的数据正在出现.
研究的目的:
- 为了比较由Omicron变种引起的肺炎的计算机断层扫描 (CT) 特征与SARS-CoV-2原始菌株相比.
- 识别不同的成像模式,可能有助于临床区分和管理.
- 为了评估两种变体在严重和严重的肺炎病例中CT得分的差异.
主要方法:
- 从诊断出原菌株或Omicron变异SARS-CoV-2肺炎的患者的医疗记录的回顾性审查.
- 两组患者之间的人口统计数据,并发症,症状,临床类型和CT特征的比较.
- 统计分析以确定CT发现的显著差异,包括地面玻璃的不透明度,整合,疯狂的铺路模式,多流和多下病变.
主要成果:
- 两组之间没有观察到年龄,性别,临床类型,症状或并发症的显著差异.
- CT特征有显著的差异 (p=0.003). 与Omicron (25.6%) 相比,原始菌株肺炎 (59.7%) 的地面玻璃不透明性更为频繁.
- 在Omicron变异性肺炎中,巩固更常见 (62.8%vs24.2%). 随着Omicron的出现,多流更频繁,而随着原始菌株的出现,多下病变更为常见.
- 与原始菌株相比,在临界和严重的Omicron-variant肺炎中,CT得分更高.
结论:
- 欧米克朗变异型的SARS-CoV-2肺炎的特征在CT扫描上是结合和肺溢出.
- 原始株SARS-CoV-2肺炎通常表现为地面玻璃的不透明度和腹膜下病变,缺乏腹膜溢出.
- CT检测结果可以帮助区分Omicron和原株SARS-CoV-2肺炎,在Omicron变种的严重和关键病例中观察到较高的CT得分.
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