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Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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Vitamins01:30

Vitamins

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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Hormones and Bone Tissue01:17

Hormones and Bone Tissue

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

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Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
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Connective Tissue Cell Types01:22

Connective Tissue Cell Types

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Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
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EFFECTS OF CHEMICAL REAGENTS ON THE CYCLIC CHANGES OF CORTEX AND CYTOPLASM IN THE ACTIVATED ENUCLEATED EGG-FRAGMENTS OF THE SEA URCHIN.

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相关实验视频

Updated: Jul 27, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

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D D 的影响

Manabu K Kojima1

  • 1Sugashima Marine Biological Laboratory, Nagoya University, Sugashima-cho, Toba-shi, Mie-ken 517, Japan.

Development, growth & differentiation
|June 7, 2023
PubMed
概括

氧化物 (D2O) 可以诱导海蛋的遗传发育,导致发育到胃肠阶段. 与D2O的联合治疗增强了这种效果,甚至激活了无核卵半个.

科学领域:

  • * 发育生物学 发育生物学
  • * * 海洋生物学 海洋生物学
  • * 细胞生物学 * 细胞生物学

背景情况:

  • *未受精的海蛋通常需要精子来激活和发育.
  • *以前的研究表明,D2O处理过的卵子的发育能力有限.
  • * 海蛋作为研究早期胚胎发育和激活的模型系统.

研究的目的:

  • * 为了研究二氧化 (D2O) 在诱导海卵中的伴生遗传发育方面的潜力.
  • * 为了比较单个和组合的D2O治疗对人工产生的有效性.
  • * 为了确定D2O是否可以激活无核的海卵碎片.

主要方法:

  • * 用氧化物 (D2O) 丰富的海水处理未受精的海蛋.
  • * 应用组合处理,包括D2O与高性海水或黄油酸.
  • *使用D2O处理来激活离心排卵的卵半部分.
  • *对胚胎发育阶段的观察和评估.

主要成果:

  • * D2O处理诱导了未受精的海卵中的受精膜升高,细胞形成和裂变.
  • *经过D2O处理的蛋发展到胃肠阶段,这与之前的报道相矛盾.
  • * 联合D2O处理 (例如,D2O+高性海水,D2O+黄油酸) 比单次D2O处理更有效.

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  • *通过D2O激活的离心排卵卵半部分发展到类似于芽细胞的阶段.

    • 结论:

    • *二氧化 (D2O) 是诱导海蛋的人工生的一种有力剂.
    • *联合D2O治疗显著增强了伴生遗传发育的诱导.
    • *D2O可以激活无核卵碎片,证明其在启动发育过程中的作用.