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Updated: Jul 27, 2025

Application of Impermeable Barriers Combined with Candidate Factor Soaked Beads to Study Inductive Signals in the Chick
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5-基氨酸对子四肢中编程细胞死亡的抑制作用: (细胞死亡/BrdU/四肢芽)

Shigenobu Toné1, Shoji Tanaka1, Yoshihiro Kato1

  • 1Department of Developmental Biology, Mitsubishi-Kasei Institute of Life Sciences, 11 Minamiooya, Machida-shi, Tokyo 194, Japan.

Development, growth & differentiation
|June 7, 2023
PubMed
概括

5-氧氨酸 (BrdU) 特别抑制了小腿中数字间介质细胞的编程细胞死亡,形成了网状结构. 提米丁阻断了这种效应,表明了BrdU.

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Inhibition of Cdk Activity02:34

Inhibition of Cdk Activity

The orderly progression of the cell cycle depends on the activation of Cdk protein by binding to its cyclin partner. However, the cell cycle must be restricted when undergoing abnormal changes. Most cancers correlate to the deregulated cell cycle, and since Cdks are a central component of the cell cycle, Cdk inhibitors are extensively studied to develop anticancer agents. For instance, cyclin D associates with several Cdks, such as Cdk 4/6, to form an active complex. The cyclin D-Cdk4/6 complex...
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