羽毛花在移植到子的肢体花时,会产生极化作用
Kohji Uchiyama1, Masako Yanazawa1, Atsushi Kuroiwa2
1Laboratory of Neuroembryology, Mitsubishi Kasei Institute of Life Sciences, 11 Minamiooya, Machida-shi, Tokyo 194, Japan.
Development, growth & differentiation
|June 7, 2023
概括
羽毛芽组织可以诱导二次身体轴在开发的四肢,表明共享的机制前后纹理之间的羽毛和四肢. 这种活动可能涉及霍克斯基因调节.
科学领域:
- 发展生物学 发展生物学
- 进化发育生物学 (Evo-Devo) 是一种发展生物学.
背景情况:
- 的同质蛋白表达 羽毛芽 镜子 肢体芽 前后轴图案.
- 这表明,在两个发育中的器官中建立两极性的潜在共享机制.
研究的目的:
- 为了调查羽毛芽组织是否与四肢芽有着共享的极化活动.
- 探索羽毛和四肢发育之间的前后轴建立的共同点.
主要方法:
- 将羽毛芽组织移植到前肢芽区域.
- 在移植后对骨元素重复和霍克斯基因表达 (Hoxd-12,Hox-13) 的分析.
- 用素进行移植预处理,以评估活动增强.
主要成果:
- 移植的羽毛芽组织诱导了肢体骨元素的镜像重复,表明极化活性.
- 前后两半的羽毛芽都显示出类似的轴诱导活性.
- 在移植部位周围协调表达了Hoxd-12和Hoxa-13,而素预处理增强了诱导.
结论:
- 羽毛芽具有极化活动的区域,类似于四肢芽的极化活动区域.
- 这种活动可能在羽毛芽轴形成中发挥作用,可能是通过霍克斯基因调节.
更多相关视频
08:04Application of Impermeable Barriers Combined with Candidate Factor Soaked Beads to Study Inductive Signals in the Chick
Published on: November 17, 2016
9.4K
08:08Chicken Recombinant Limbs Assay to Understand Morphogenesis, Patterning, and Early Steps in Cell Differentiation
Published on: January 12, 2022
2.3K
相关概念视频
Gastrulation
Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...
Background and Environment Affect Phenotype
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
