由于在海中冷却而引起的胃外排气 虫幼虫
T Takahashi1, M Hoshi1, É Asahina1
1Zoological Institute and The Institute of Low Temperature Science, Hokkaido University, Sapporo, 060 Japan.
Development, growth & differentiation
|June 7, 2023
概括
冷却海刺胚胎可以通过影响二级介质细胞伪体诱导外胃. 这一过程也由某些药物触发,突出显示了微管在海发展中的作用.
科学领域:
- 发育生物学是发展生物学.
- 海洋生物学 海洋生物学
- 皮研究研究皮研究.
背景情况:
- 异常发育过程 - - 胃外流 (exogastrulation) 可以在海膽胚胎中引起.
- 了解外胃排泄的机制对于理解海的正常发育至关重要.
研究的目的:
- 通过冷却和化学处理,研究各种海鱼物种诱导外胃化.
- 阐明导致冷却诱导的胃外流的细胞和分子机制.
主要方法:
- 在化过程中将海胚胎 (Strongylocentrotus物种,Pseudocentrotus depressus,Anthocidaris crassispina) 暴露在低温下.
- 用微管破坏剂对幼虫的治疗:胆固醇,维布拉斯,细胞素B和细胞素C.
- 微观观察二次介质细胞行为和体形态.
主要成果:
- 冷却诱导了几种海的外胃,主要是通过防止伪的形成或引起它们的退出和腹收缩.
- 药物治疗也成功诱导出胃外流,这表明涉及细胞骨破坏的常见机制.
- 胃化的阶段影响了冷却的有效性,后来的阶段表现出较少的易感性.
结论:
- 低温和特定的药物破坏了二次介质细胞中的微管功能,导致海的外胃化.
- 这些发现表明,环境温度和海繁殖期间的发育过程之间存在联系.
- 外胃刺激诱导提供了关于胃刺激和细胞与细胞相互作用的细胞机制的见解.
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