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Updated: Jul 27, 2025

Xenopus laevis as a Model to Identify Translation Impairment

Xenopus laevis as a Model to Identify Translation Impairment

Published on: September 27, 2015

在XENOPUS LAEVIS中对整个OOGENESIS的运动分析

J C Callen¹, N Dennebouy¹, J C Mounolou¹

¹Laboratoire de Biologie Générale. Bâtiment 400, Université de Paris-Sud, 91405 ORSAY France.

Development, growth & differentiation

|June 7, 2023

概括

在没有激素刺激的情况下,雌性Xenopus laevis需要两年的卵细胞成熟. 大多数卵子在250微米时停止发育,这表明卵子发生过程中的关键检查点.

科学领域:

发展生物学发展生物学
生殖生物学生殖生物学
谢诺普斯·莱维斯科研研究

背景情况:

在Xenopus laevis的卵细胞成熟是一个复杂的过程.
了解 oogenesis 时间对于生殖研究至关重要.

研究的目的:

详细介绍Xenopus laevis.卵细胞生长的时间表和不同阶段.
为了确定关键的发育阶段和潜在的瓶在 oogenesis.

主要方法:

在标准繁殖条件下观察Xenopus laevis的卵细胞发育.
在变形后的不同时间点测量卵细胞直径.
根据生长速度和大小,区分生长过程的不同阶段.

主要成果:

雌性Xenopus laevis需要两年的转化后才能产生成熟的卵子.
产卵形成包括四个不同的生长阶段,在250-300μm (后期I阶段) 显著放缓.
大多数卵细胞没有完成完整的生长周期,在大约250微米时停止生长.

结论:

在Xenopus laevis的卵细胞发育是一个漫长的过程,有明确的阶段.
250微米的卵细胞大小代表了一个关键的发育检查点.
仔细测量卵细胞大小对于准确的生化分析和比较研究至关重要.

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Oogenesis

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...