相关实验视频
Updated: Jul 27, 2025

12:21
Feeder-free Derivation of Melanocytes from Human Pluripotent Stem Cells
Published on: March 3, 2016
10.4K
阴道阿斯基的胚胎发生过程中脑质细胞的发育: (阴道发育/脑质细胞的分化/卵子活性/进化)
Billie J Swalla1, William R Jeffery1
1Department of Zoology and Bodega Marine Laboratory, University of California, Davis, P. O. Box 247, Bodega Bay, CA 94923 U.S.A.
Development, growth & differentiation
|June 7, 2023
概括
在Bostrichobranchus digonas中,状的发育表明胚胎缺乏典型的幼虫特征,但发展出独特的铁酶阳性细胞. 这表明,从一个有尾巴的阿斯基迪亚祖先进化,解开urodele特征.
科学领域:
- 发展生物学 发展生物学
- 进化生物学 进化生物学
- 海洋生物学 海洋生物学
背景情况:
- 虫表现出多样化的发育策略,包括 (非尾巴) 和urodele (尾巴) 幼虫形式.
- 波斯特里科布朗克斯 (Bostrichobranchus digonas) 是一种卵生的鼻,胚胎在内部发育.
- 了解部发育提供了对进化途径和幼虫结构的损失或修改的见解.
研究的目的:
- 为了研究Bostrichobranchus digonas的部发育.
- 为了确定B. digonas胚胎中分化细胞和组织的特定分子标记物.
- 通过将发育特征与urodele ascidians的特征进行比较,探索鼻的进化起源.
主要方法:
- 对B. digonas.中的卵,胚胎和幼虫进行形态检查.
- 利用特定的分子标记物来检测分化的urodele ascidian幼虫细胞和组织.
- 分析了肌肉特异性标记物的表达 (乙胆酶,α-actin,肌重链) 和铁酶.
主要成果:
- B. digonas 胚胎缺乏典型的 urodele 幼虫特征,包括一条记带和分化的肌肉细胞.
- 在B. digonas胚胎中,肌肉特异性标记表达无法检测到.
- 胚胎在黑色素细胞前体中表现出铁酶的表达,形成一个暂时的脑色素细胞,并在转化后出现了铁酶阳性细胞.
结论:
- 不同的urodele发育特征可以在神经发育过程中独立 (不结合) 演变.
- 遗留的大脑黑色素细胞的存在表明,B. digonas从一个urodele祖先进化.
- 这项研究突出了类进化中的发育途径的可塑性.
相关概念视频
Multipotency and Niche of Bulge Stem Cell
3.7K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
3.7K
Pigmentation
2.5K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
2.5K

