含有活性氧的抗菌效果与其他牙膏对抗抗菌效果的比较评估
Tanvi Jindal1, Nikhil Srivastava1, Vivek Rana1
1Department of Pediatric and Preventive Dentistry, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India.
概括
这项研究发现,活性氧 (AO) 牙膏在儿童早期牙 (ECC) 的儿童中有效降低突变性 estreptococcus (SM). 虽然AO显示出比一些非化选项更好的结果,但它并不优于氨基化物 (AF) 牙膏.
科学领域:
- 儿科牙科 儿科牙科
- 微生物学 微生物学
- 皮肤病学 皮肤病学 皮肤病学
背景情况:
- 化牙膏是传统的牙预防方法.
- 对化物的担忧引发了对非化替代品的兴趣.
- 减少Streptococcus mutans (SM) 是管理早期儿童 (ECC) 的关键.
研究的目的:
- 为了比较基于活性氧 (AO) 的牙膏与其他配方的抗菌疗效.
- 评估包括氨基化物 (AF),单酸 (SMP),草药 (HB) 和三酸 (TCP) 在内的牙膏.
- 评估诊断为ECC的儿童对MS数量的影响.
主要方法:
- 一项随机对照试验,涉及250名年龄在3-6岁的儿童,患有ECC (def ≥4).
- 参与者被分为五组,使用AO,TCP,SMP,AF或HB牙膏.
- 唾液样本在基线和15天后每天刷两次以检测SM殖民地数量.
主要成果:
- 所有测试的牙膏都显著降低了MS数量 (P < 0.001).
- 与AF相比,AO牙膏显示显著减少 (P = 0.017).与AF相比,AO牙膏显示明显减少 (P = 0.017).
- 在AO和TCP,SMP或HB牙膏之间没有发现显著差异.
结论:
- 所有评估的牙膏都在减少ECC儿童的MS中表现出有效性.
- 与SMP,TCP和HB配方相比,AO牙膏表现出更好的结果.
- AO牙膏没有被证明比AF牙膏更有效.
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