[两个人的Folie - 血栓和感染]
Julia Picker1,2, Johannes Schwenke1,2, Lorenz Neuenschwander1
1Medizinische Universitätsklinik, Infektiologie und Spitalhygiene, Kantonsspital Baselland, Bruderholz, Universität Basel, Basel, Schweiz.
Praxis
|June 7, 2023
概括
感染显著增加了静脉血栓栓塞 (VTE) 和动脉血栓塞的风险,甚至在感染后持续长达一年. 感染的严重程度与增加的VTE风险相关.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 血栓形成的原因之一是血栓形成.
背景情况:
- 感染往往被忽视为血栓栓塞事件的危险因素.
- 已知静脉血栓塞栓症 (VTE) 的风险因素包括固定,手术和瘤.
- 感染对VTE风险的影响与已确定的风险因素相当.
研究的目的:
- 突出感染在促进静脉和动脉血栓栓塞的重要作用.
- 要强调感染诱导的静脉瘤风险可能是长期的,持续6-12个月.
- 在感染的背景下讨论动脉血栓栓塞的管理,特别是心房动.
主要方法:
- 审查现有的文献和临床数据,将感染与血栓栓塞事件联系起来.
- 分析与感染相关的VTE风险的持续性和严重性依赖性.
- 评估与肺炎等特定感染相关的心血管事件.
主要成果:
- 感染增加了VTE风险,与固定或手术等传统因素相似.
- 感染后静脉瘤风险升高可能持续6-12个月.
- 感染还会促进动脉血栓栓塞,肺炎与急性心血管事件相关,在20%的病例中.
结论:
- 感染代表了对VTE和动脉血栓栓塞的关键,经常被低估的风险因素.
- CHA2DS2 VASc评分是一个可靠的工具,用于指导感染相关心房动的抗凝血治疗.
- 血栓栓塞栓风险的临床评估应该经常考虑最近或活跃的感染.
相关概念视频
Anticoagulant Drugs: Low-Molecular-Weight Heparins
767
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
767
Venous Thrombosis I: Introduction
14
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
14
Disorders of Hemostasis
1.0K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
1.0K
Clot Retraction and Fibrinolysis
6.5K
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
6.5K
Venous Thrombosis III: Interprofessional Care
11
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
11
Coagulation
7.2K
The coagulation phase is a critical part of the body's process to prevent blood loss following injury to blood vessels. It involves chemical reactions that form a clot to seal the injured area. The clotting process begins shortly after injury, within 15-20 seconds for severe damage and 1-2 minutes for minor injuries.
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
7.2K


