附录中的新生体
Franziska Köhler1, Niels Matthes, Mathias Rosenfeldt
1Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital of Würzburg, Germany; Comprehensive Cancer Center Mainfranken, University Hospital of Würzburg, Germany; Institute of Pathology, University of Würzburg, Germany; Medical Clinic and Polyclinic II, University Hospital of Würzburg, Germany; Department of Biochemistry and Molecular Biology, University of Würzburg, Germany.
Deutsches Arzteblatt international
|June 7, 2023
概括
尾瘤是罕见但多样化的,需要根据类型和阶段进行量身定制的治疗. 手术方法范围从尾切除术到半尾切除术,化学疗法只适用于晚期.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 病理学 病理学 病理学
背景情况:
- 虫状尾的新生体并不常见,呈现出各种各样的病理实体.
- 这些瘤仅占胃肠道恶性瘤的一小部分,因此需要具体的治疗策略.
研究的目的:
- 审查和综合目前关于尾瘤诊断和治疗的知识.
- 根据组织病理学分类和瘤阶段,为选择适当的治疗干预提供指导.
主要方法:
- 在PubMed,Embase和Cochrane数据库中进行了选择性的文献搜索.
- 审查了出版物,以确定关于尾瘤特征和治疗结果的关键发现.
主要成果:
- 尾瘤包括腺瘤,状病变,腺癌,杯状细胞腺癌,粘膜瘤和神经内分泌瘤.
- 治疗方法各不相同:尾切除术用于腺瘤和小神经内分泌瘤,血切除术用于腺癌和高风险的神经内分泌瘤,以及用HIPEC进行细胞还原手术用于粘膜性瘤.
- 系统化疗通常没有益处,除了晚期 (III+) 腺癌和杯状细胞腺癌.
结论:
- 尾瘤的有效管理依赖于准确的组织病理学诊断和分期.
- 治疗策略必须是个性化的,从微创手术到彻底的瘤切除和辅助疗法.
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