预孕和产前孕产妇压力与年轻成年人广泛的自闭症表型有关:项目冰风暴项目
Xinyuan Li1,2, David P Laplante3, Guillaume Elgbeili2
1Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada.
概括
产前孕产妇压力 (PNMS) 可能会影响年轻人的广泛自闭症表型 (BAP). 不同类型的母亲压力与特定的BAP特征有关,如疏远,务实的语言和硬的个性.
科学领域:
- 发展心理学 发展心理学
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
背景情况:
- 在产前母亲压力 (PNMS) 和儿童自闭症之间存在已确定的联系.
- 较少的研究已经探索了PNMS和年轻成年人的广泛自闭症表型 (BAP) 之间的联系.
- BAP包括亚临床特征,如疏远的人格,务实语言障碍和刚性人格.
研究的目的:
- 调查PNMS的不同方面是否与年轻成年后代的特定BAP领域有关.
- 检查由不同维度的孕产妇压力解释的BAP特征的差异.
主要方法:
- 在1998年的北克冰暴危机期间招募了孕妇,并评估了三个压力方面:客观困难,主观痛苦和认知评估.
- 在19岁时使用BAP自我报告问卷评估年轻成年后代 (n=33岁).
- 采用线性和逻辑回归分析来确定PNMS和BAP特征之间的关联.
主要成果:
- 孕产妇的压力因素解释了总BAP分数及其领域的差异高达21.4%.
- 客观困难与疏远的人格 (16.8%的差异) 和硬的人格 (20.0%的差异) 有关.
- 主观困扰与实用语言障碍 (15.1%的差异),认知评估与刚性人格 (14.3%的差异) 相关.
结论:
- 产前母亲压力的不同方面可能会对年轻成年人广泛的自闭症表型的特定组成部分产生不同的影响.
- 研究结果表明,怀孕期间母亲的压力与晚年BAP特征之间存在微妙的关系.
- 由于该研究的样本规模较小,应谨慎解释结果.
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