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Updated: Jul 27, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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[在坦辛生物合成途径中C20氧化酶的修改]

Xiao-Qing Cao1, Xiao-Hui Ma1, Ya-Tian Cheng2

  • 1Yunnan Key Laboratory of Sustainable Utilization of Southern Medicine, College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine Kunming 650500, China.

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
|June 7, 2023
PubMed
概括

通过修改CYP76AK1酶,提升了传统中医药中用于心血管健康的关键化合物坦辛的微生物生产. 这项研究确定了增强酶功能的关键部位,改善了tanshinone的合成.

关键词:
11-氧苏醇的使用方法不断氧化的持续氧化过程.细胞染色体P450的使用.指导进化是指导进化的.突变物是突变物中的一个.

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