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更薄的子宫内膜与新生儿出生时体重较低有关
Xiuping Zhang1, Lixia Liang1, Yuanjing Hu2
1Center of Reproductive Medicine, Children's Hospital of Shanxi and Women Health Center of Shanxi, Taiyuan, China.
概括
胚胎移植前的子宫内膜厚度 (EMT) 在IVF-FET周期中影响新生儿出生体重. 较厚的子宫内膜与较高的出生体重相关,这表明EMT优化可以改善新生儿的结果.
科学领域:
- 生殖医学 生殖医学
- 新生儿健康 新生儿健康
- 在体外受精过程中受精.
背景情况:
- 子宫内膜厚度 (EMT) 是成功植入胚胎的一个关键因素.
- 优化EMT对于改善妊娠和新生儿在辅助生殖技术中的结果至关重要.
研究的目的:
- 在接受体外受精-冷胚胎移植 (IVF-FET) 的妇女中,研究胚胎移植前子宫内膜厚度 (EMT) 与新生儿出生体重之间的关联.
主要方法:
- 在2015年6月至2019年2月期间,对IVF-FET后单子活产的回顾性分析.
- 收集了关于母亲年龄,新生儿结局 (出生体重,妊娠年龄,分娩方式,低出生体重百分比,巨病发病率) 和母亲并发症的数据.
主要成果:
- 由EMT>12毫米的患者分娩的单体新生儿的出生体重明显高于具有较薄子宫内膜的新生儿.
- 平均出生体重随着EMT类别的增加而增加 (EMT<8毫米,8-12毫米,≥12毫米).
- 出生体重的独立预测因素包括母亲的高血压,膜的过早破裂,胎盘前,新生儿的性别,妊娠年龄,分娩方式,转移的胚胎数量和荷尔蒙水平.
结论:
- 新生儿出生体重与第一个FET周期胚胎移植前的子宫内膜厚度显著相关.
- 在新生儿中观察到较低的出生体重,这些新生儿来自具有较薄子宫内膜的患者.
- 在胚胎移植之前增强子宫内膜厚度可能是一个可行的策略,以改善新生儿在生育治疗中的结果.
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