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Updated: Jul 27, 2025

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UdgX的突变和结构分析:对活动站点口袋架构及其演变的洞察

Shashanka Aroli1, Eui-Jeon Woo2,3, Balasubramanian Gopal4

  • 1Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.

Nucleic acids research
|June 7, 2023
PubMed
概括

一种 uracil 产生的酶 UdgX 使用独特的 R 循环结构. 突变显示H109和E52是其催化活性的关键,而Q53稳定了R循环,使其与其他UDG区分开来.

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