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Updated: Jul 27, 2025

An In Ovo Model for Testing Insulin-mimetic Compounds
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来自植物的天然产品,针对未来开发抗糖尿病药物的关键酶

R Mata1, L Flores-Bocanegra1, B Ovalle-Magallanes1

  • 1Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Mexico City, 04510, Mexico. rachel@unam.mx.

Natural product reports
|June 7, 2023
PubMed
概括

药用植物提供天然化合物,可以被开发成抗糖尿病剂. 本综述涵盖了植物衍生抑制剂,其向涉及葡萄糖恒温的关键酶.

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α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
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