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Updated: Jul 27, 2025

Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing
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Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing

Published on: October 16, 2018

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在两个精英控制者中,正在进行的HIV-1进化和储存库再种植,具有遗传多样性的外围前病毒准物种

Suwellen Sardinha Dias de Azevedo1, Fernanda Heloise Côrtes1, Larissa M Villela2

  • 1Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de AIDS & Imunologia Molecular, Rio de Janeiro, RJ, Brasil.

Memorias do Instituto Oswaldo Cruz
|June 7, 2023
PubMed
概括

精英控制器 (EC) 保持低的人类免疫缺陷病毒 (HIV) 负载. 一些具有多样化的HIV储存库的EC显示正在进行的病毒演变和重新播种,表明尽管病毒性不检测到,但病毒活动仍然持久.

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