在怀孕期间接种疫苗
Anwar H Nassar1, Elie Hobeika1, Dina Chamsy1
1Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
概括
孕妇面临感染性疾病的更高风险. 这篇评论讨论了流感,Tdap和COVID-19等基本疫苗,以及保护母亲和新生儿的未来选择.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 怀孕改变了免疫反应,增加了对严重传染病的易感性.
- 流感和百日咳对母亲和新生儿的健康构成重大风险.
- 随着COVID-19的爆发,人们需要在怀孕期间更新疫苗接种策略.
研究的目的:
- 审查目前针对孕妇的疫苗接种建议.
- 讨论在怀孕期间支持疫苗的理由和证据.
- 探索新兴疫苗用于围产期感染预防.
主要方法:
- 对已发表的研究和关于怀孕期间疫苗的指导方针的文献综述.
- 对孕妇人口感染性疾病严重程度的流行病学数据的分析.
- 讨论专家建议和临床试验结果.
主要成果:
- 在怀孕期间,常规建议接种流感和Tdap疫苗.
- 现在建议所有孕妇接种COVID-19疫苗.
- 根据风险效益分析,可以考虑为高风险人群提供额外的疫苗.
结论:
- 疫苗接种是保护孕妇及其婴儿免受传染病的关键工具.
- 目前正在进行的研究和开发有望开发新的疫苗,进一步降低围产死亡率.
- 基于证据的建议指导着在整个怀孕期间安全有效地使用疫苗.
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