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Updated: Jul 27, 2025

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
06:07

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors

Published on: August 5, 2022

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确定E2F1-RAD51AP1轴作为MGMT甲基化GBMTMZ抗性的关键因素

Junhu Zhou1,2, Fei Tong1,2, Jixing Zhao1,2

  • 1Tianjin Medical University General Hospital, Tianjin 300052, China.

Cancer biology & medicine
|June 7, 2023
PubMed
概括

这项研究揭示了E2F1和RAD51AP1作为质母细胞瘤对EGFRvIII和temozolomide (TMZ) 耐药性的关键因素. 向RAD51AP1可能会改善特定的GBM患者群体的TMZ治疗有效性.

关键词:
E2F1 E2F1 E2F1 E2F1 E2F1 E2F1 E2F1 E2F1 E2F1欧洲农业基金第八.在MGMT中,我们可以看到MGMT.在RAD51AP1中使用.在TMZ中,我们可以看到TMZ.

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