在COVID-19中脑血管疾病:系统审查和元分析
Ritesh G Menezes1, Tamim Omar Alabduladhem2, Ahmed Kamal Siddiqi3
1Department of Pathology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Le infezioni in medicina
|June 7, 2023
概括
COVID-19 感染显著增加了急性脑血管疾病 (CVD) 的风险,特别是心血管和密码性中风. 预先存在的疾病,如心房动,心脏病,糖尿病和高血压,在COVID-19患者中增加了这种风险.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- COVID-19与急性脑血管疾病 (CVD) 之间的联系需要进一步调查.
- 新出现的数据表明,这可能会改变以前的理解.
研究的目的:
- 系统地评估COVID-19诊断的患者中风的发生率和特征.
- 为了确定特定的中风病因和与COVID-19感染相关的风险因素.
主要方法:
- 在PubMed数据库进行了全面的文献搜索,截至2022年2月.
- 对37项涉及294,249名患者的研究进行了元分析,使用随机效应模型进行了分析.
- 结果以几率比率 (ORs) 呈现,有95%的置信区间 (95%CI).
主要成果:
- 在COVID-19患者中,急性心血管疾病的发生率为2.6% (95%CI:2.0-3.3).
- COVID-19阳性与心血管 (OR=14.15) 和密码性 (OR=2.87) 中风病因有很强的关联.
- 确定的主要危险因素包括心房动 (OR=2.60),冠状动脉疾病 (OR=2.24),糖尿病 (OR=2.46) 和高血压 (OR=3.65).
结论:
- COVID-19 感染与急性脑血管事件的风险增加有关.
- 这项研究强调了COVID-19与心血管栓塞性和密码性中风类型的关联.
- 已确定的风险因素,如心房动,冠状动脉疾病,糖尿病和高血压加剧了COVID-19患者的心血管疾病风险.
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