Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jul 27, 2025

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates
08:41

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

Published on: July 17, 2020

5.0K

灵长类人皮层网络中的光遗传学

Sam Merlin1, Trichur Vidyasagar2,3

  • 1Medical Science, School of Science, Western Sydney University, Campbelltown, NSW, Australia.

Frontiers in neuroanatomy
|June 7, 2023
PubMed
概括
此摘要是机器生成的。

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Primate V2 Receptive Fields Derived from Anatomically Identified Large-Scale V1 Inputs.

Research square·2024
Same author

Primate V2 Receptive Fields Derived from Anatomically Identified Large-Scale V1 Inputs.

bioRxiv : the preprint server for biology·2024
Same author

Antioxidant Behavioural Phenotype in the <i>Immp2l</i> Gene Knock-Out Mouse.

Genes·2023
Same author

Immp2l knockdown in male mice increases stimulus-driven instrumental behaviour but does not alter goal-directed learning or neuron density in cortico-striatal circuits in a model of Tourette syndrome and autism spectrum disorder.

Behavioural brain research·2023
Same author

Habitual behaviour associated with exposure to high-calorie diet is prevented by an orexin-receptor-1 antagonist.

Addiction neuroscience·2023
Same author

Targeting the lateral hypothalamus with short hairpin RNAs reduces habitual behaviour following extended instrumental training in rats.

Neurobiology of learning and memory·2022
Same journal

Editorial: Updates and discussions about basal ganglia and their circuits.

Frontiers in neuroanatomy·2026
Same journal

TC2-Res: a structured fusion of tract-level and connectome-level brain imaging in small-sample cohorts of athletes.

Frontiers in neuroanatomy·2026
Same journal

Revisiting the clastosome: a stress-induced nuclear proteolytic compartment of mammalian cells.

Frontiers in neuroanatomy·2026
Same journal

Intrinsic elaboration of prefrontal modularity: a dual-control model of axon bundling and synaptic docking.

Frontiers in neuroanatomy·2026
Same journal

Selective enrichment of TCF4 in GABAergic neurons during postnatal primate development.

Frontiers in neuroanatomy·2026
Same journal

ATF3-based peripheral neural tract tracing.

Frontiers in neuroanatomy·2026
查看所有相关文章

非人类灵长类动物的光遗传学正在进步,克服了遗传和分娩方面的挑战. 它提供了一个强大的工具来补充研究复杂神经电路的现有方法.

科学领域:

  • 神经科学是一个神经科学.
  • 系统神经科学 系统神经科学
  • 灵长类动物研究研究

背景情况:

  • 在非人类灵长类动物中实施光遗传学面临着重大挑战.
  • 此前的研究受到了遗传处理能力和光输送限制的阻碍.
  • 灵长类动物中复杂的神经回路存在独特的研究障碍.

研究的目的:

  • 审查光遗传学在灵长类研究中的进展和挑战.
  • 突出新技术如何克服以前的局限性.
  • 提出光遗传学作为系统神经科学的补充工具.

主要方法:

  • 利用定制的病毒载体和促进器来增强灵长类动物的基因表达.
  • 采用可植入的微LED阵列用于更深层的大脑组织的光输送.
  • 结合Cre-表达和Cre-依赖向量以实现精确的电路准.

主要成果:

  • 最近的成功证明了光遗传学在灵长类动物中的可行性和日益广泛的应用.
  • 先进的技术允许在复杂的神经回路内进行更具体的准.
  • 光遗传学现在可以有效地准更深层的大脑结构.

结论:

关键词:
电力生理学 电力生理学神经电路的神经电路.非人类的灵长类灵长类动物.视觉遗传学 视觉遗传学系统神经科学神经科学

更多相关视频

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates
08:32

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates

Published on: October 3, 2017

8.1K
Injections of AAV Vectors for Optogenetics in Anesthetized and Awake Behaving Non-Human Primate Brain
09:42

Injections of AAV Vectors for Optogenetics in Anesthetized and Awake Behaving Non-Human Primate Brain

Published on: August 4, 2021

3.7K

相关实验视频

Last Updated: Jul 27, 2025

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates
08:41

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

Published on: July 17, 2020

5.0K
Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates
08:32

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates

Published on: October 3, 2017

8.1K
Injections of AAV Vectors for Optogenetics in Anesthetized and Awake Behaving Non-Human Primate Brain
09:42

Injections of AAV Vectors for Optogenetics in Anesthetized and Awake Behaving Non-Human Primate Brain

Published on: August 4, 2021

3.7K
  • 光遗传学正变得越来越适用于灵长类神经科学研究.
  • 新方法解决了灵长类大脑研究中的遗传和解剖学挑战.
  • 当光遗传学被用来补充传统的神经科学技术时,它是最有利的.