肥胖患者的良好控制与不良控制的糖尿病:MRI评估的胰腺脂肪含量差异
Xin Yu1, Yan-Hao Huang1, You-Zhen Feng1
1Medical Imaging Center, First Affiliated Hospital of Jinan University, Guangzhou, China.
Quantitative imaging in medicine and surgery
|June 7, 2023
概括
胰腺尾部脂肪增加与2型糖尿病 (T2D) 肥胖患者的血糖控制不佳有关. 腹腔外科手术有效地改善T2D控制,并减少子宫外脂肪沉积.
科学领域:
- 医疗成像医学成像
- 内分泌学 在内分泌学.
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 肥胖和2型糖尿病 (T2D) 增加了糖尿病并发症的风险.
- 内脏脂肪组织 (VAT),肝脏和胰腺脂肪沉积物与代谢功能障碍有关.
研究的目的:
- 研究VAT,肝脏和胰腺脂肪分数与肥胖T2D患者的血糖控制之间的关联.
- 评估减肥手术对血糖控制和子宫外脂肪的代谢影响.
主要方法:
- 对151名肥胖患者 (2019年7月至2021年3月) 的回顾性横截面研究,其葡萄糖耐受性有所变化.
- 磁共振成像 (MRI) 使用IDEAL-IQ定量增值税,肝脏PDFF和胰腺PDFF.
- 分析包括单变量和多变量回归,其中一个子集评估了腹膜外科手术前和后的情况.
主要成果:
- 在葡萄糖耐受性组中观察到VAT,肝脏和胰腺脂肪分数的显著差异.
- 胰腺尾部PDFF在控制不良的T2D中明显高于控制良好的T2D.
- 多变量分析确定胰腺尾部PDFF是血糖控制不良的重要预测因素 (OR=2.09,P=0.022).
结论:
- 胰腺尾部脂肪升高与T2D肥胖个体的低血糖控制有很强的相关性.
- 腹腔外科手术在改善血糖控制和减少肥胖患者的子宫外脂肪方面表现出有效性,糖尿病控制不良.
相关概念视频
01:36Carbohydrate Metabolism
11.3K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.3K
01:29Chronic Pancreatitis II: Collaborative Care
116
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
116