迷幻后照现象:对经典的血清激素类迷幻药物亚急性作用的系统审查
Ricarda Evens1,2,3, Marianna Elisa Schmidt4, Tomislav Majić2,5
1Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.
Therapeutic advances in psychopharmacology
|June 7, 2023
概括
迷幻药物可能会引起积极的"后照",症状减少,幸福感增加. 发现了包括头痛和睡眠问题在内的亚急性影响,这需要进一步研究长期益处.
科学领域:
- 心理药理学 心理药理学
- 神经科学是一个神经科学.
- 心理健康研究 心理健康研究
背景情况:
- 经典的赛洛类迷幻药与持续的亚急性效应有关,称为"迷幻后光".
- 这种后发光现象被假设在亚急性期间增强心理治疗干预.
- 了解这些亚急性影响对于治疗应用至关重要.
研究的目的:
- 系统地审查经典血清激素类迷幻药的亚急性影响.
- 为了提供心理结局和心理使用后1天至1个月发生的不良影响的概述.
主要方法:
- 对1950年至2021年8月期间发表的研究进行系统审查.
- 搜索了MEDLINE和科学网络的核心集合,用于迷幻 (LSD, псилоцибин,DMT,5-MeO-DMT,梅斯卡林,阿雅华斯卡) 研究.
- 包括评估人类成年人的心理结果和亚急性不良影响的研究.
主要成果:
- 他们审查了48项涉及1774名参与者的研究.
- 观察到的效应包括减少精神病理症状,增加幸福感,情绪,正念,社会措施,灵性和积极的行为变化.
- 亚急性不良反应包括头痛,睡眠障碍和心理困扰;没有报告严重不良事件.
结论:
- 研究结果支持亚急性迷幻"后照"的存在,对自我,他人和环境感知有潜在的有益变化.
- 亚急性不良事件通常为轻度至重度,尽管通常缺乏标准化的评估.
- 需要进一步的研究来探索调节变量和将亚急性影响整合为长期心理健康益处.
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