Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Gene Therapy00:59

Gene Therapy

25.6K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
25.6K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

73
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
73
What is Genetic Engineering?00:49

What is Genetic Engineering?

74.4K
Overview
74.4K
Recombinant DNA01:09

Recombinant DNA

96.0K
Overview
96.0K
The Central Dogma01:20

The Central Dogma

23.0K
The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
23.0K
Transgenic Organisms00:53

Transgenic Organisms

31.4K
Overview
31.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Network-based integrative transcriptomic analysis reveals immune-regulatory and oncogenic signatures of EOMES and SPRYD3 in head and neck squamous cell carcinoma.

BMC cancer·2026
Same author

Hypoxia-preconditioned adipose-derived mesenchymal stem cells-derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5-mediated inactivation of TLR4/NF-κB/NLRP3 inflammatory signaling.

Journal of diabetes investigation·2026
Same author

Applications of polysaccharide hydrogels in wound healing and immune regulation.

International journal of biological macromolecules·2026
Same author

Differences in inpatient hypertension management practices between specialists and non-specialists in Zhejiang Province, China.

Blood pressure·2026
Same author

<i>Fraxinus mandshurica SPL2</i> enhances tolerance to drought stress by activating the phenylpropanoid pathway.

Forestry research·2026
Same author

A self-powered chloroplast-driven nanophotosystem for treating skin photoaging through rejuvenating mitochondria and revitalizing senescent fibroblasts.

Journal of nanobiotechnology·2026
Same journal

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management.

MedComm·2026
Same journal

Metabolic Dysfunction-Associated Fatty Liver Disease: From Pathogenesis to Treatment.

MedComm·2026
Same journal

Dexmedetomidine Rapidly Relieves Stress-Induced Hyperalgesia via Presynaptic <i>α</i>2-Adrenergic Inhibition at Orbitofrontal-Insular Glutamatergic Synapses.

MedComm·2026
Same journal

Osteoarthritis: Epidemiology, Diagnosis, and Treatment.

MedComm·2026
Same journal

Multiomics Identification and Validation of an Integrin-Extracellular Matrix Network Driving Respiratory Syncytial Virus-Induced Lung Injury and Repair.

MedComm·2026
Same journal

A Low Serum Calcium-to-Potassium Ratio Predicts Postpartum Venous Thromboembolism Risk: Mediation by Hemoglobin and D-Dimer in a Multicenter Cohort.

MedComm·2026
查看所有相关文章

相关实验视频

Updated: Jul 27, 2025

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers
12:30

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Published on: August 12, 2014

9.9K

基于生物材料的基因疗法

Yi Yu1, Yijun Gao1, Liming He2

  • 1Department of Stomatology The Second Xiangya Hospital Central South University Changsha China.

MedComm
|June 7, 2023
PubMed
概括
此摘要是机器生成的。

生物材料为基因治疗提供了比病毒载体更安全的替代方案,改善了核酸的输送和稳定性. 本综述探讨了基于生物材料的系统,用于治疗癌症和遗传疾病等复杂疾病.

关键词:
生物材料是一种生物材料.基因治疗的基因疗法非病毒载体的非病毒载体.病毒载体病毒载体

更多相关视频

Electroporation-Based Genetic Modification of Primary Human Pigment Epithelial Cells Using the Sleeping Beauty Transposon System
07:04

Electroporation-Based Genetic Modification of Primary Human Pigment Epithelial Cells Using the Sleeping Beauty Transposon System

Published on: February 4, 2021

2.1K
A GMP-Compliant Procedure for the Generation of Gene-Modified T cells
06:47

A GMP-Compliant Procedure for the Generation of Gene-Modified T cells

Published on: October 6, 2023

631

相关实验视频

Last Updated: Jul 27, 2025

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers
12:30

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

Published on: August 12, 2014

9.9K
Electroporation-Based Genetic Modification of Primary Human Pigment Epithelial Cells Using the Sleeping Beauty Transposon System
07:04

Electroporation-Based Genetic Modification of Primary Human Pigment Epithelial Cells Using the Sleeping Beauty Transposon System

Published on: February 4, 2021

2.1K
A GMP-Compliant Procedure for the Generation of Gene-Modified T cells
06:47

A GMP-Compliant Procedure for the Generation of Gene-Modified T cells

Published on: October 6, 2023

631

科学领域:

  • 生物医学工程 生物医学工程
  • 分子生物学分子生物学
  • 基因治疗 基因治疗

背景情况:

  • 基因疗法纠正缺陷基因,用于治疗遗传性疾病,癌症和免疫系统疾病.
  • 传统的病毒载体面临着免疫性和感染风险等挑战.
  • 核酸需要有效的输送系统来克服降解和细胞膜障碍.

研究的目的:

  • 审查基因疗法模式的最新进展.
  • 讨论核酸输送策略,强调基于生物材料的系统.
  • 总结基于生物材料的基因疗法的当前应用.

主要方法:

  • 对基因疗法发展的文献综述.
  • 核酸输送挑战和解决方案的分析.
  • 专注于生物材料在基因传递中的应用.

主要成果:

  • 生物材料增强了核酸的稳定性和细胞内传递效率.
  • 基于生物材料的载体减轻了与病毒载体相关的风险.
  • 这些系统显示出治疗各种复杂疾病的前景.

结论:

  • 基于生物材料的基因传递系统代表了治疗策略的重大进步.
  • 与传统的病毒载体相比,它们提供了更安全,更有效的方法.
  • 这些系统的进一步研究和应用对于疾病治疗至关重要.