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Updated: Jul 27, 2025

High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method
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综合的体外分析评估了与rifabutin相比,rifampicin的药物相互作用风险的变量

Julie Nilles1,2, Johanna Weiss1, Max Sauter1

  • 1Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

Archives of toxicology
|June 7, 2023
PubMed
概括

里法素和里法布丁在它们如何影响CYP3A4和P-糖蛋白 (Pgp) 等药物代谢酶方面有所不同. 里法布丁是一种较弱的诱导剂,但是一种强大的PGP抑制剂,这解释了其较低的药物相互作用风险.

关键词:
在ABCB1中,ABCB1是ABCB1.在 CYP3A4 中.诱导是一种诱导.在Pgp中,Pgp是指Pgp的意思.里法布丁 (Rifabutin) 是一种药物.里法皮辛 (Rifampicin) 是一种药物.

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