相关实验视频
Updated: Jul 27, 2025

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Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
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镇静和止痛药用于减少儿科伊利奥科里克内接收
Naveen Poonai1, Daniel M Cohen2, Doug MacDowell2
1Departments of Pediatrics, Internal Medicine, Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
JAMA network open
|June 7, 2023
概括
大多数患有大耳内缩减症的儿童没有得到止痛或镇静. 这些干预措施与穿孔或未能减少无关,质疑当前的做法.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 临床结果 临床结果
背景情况:
- 伊利奥科利性肠是儿童肠道阻塞的常见原因之一.
- 通过空气或液体阴道减少是标准的,但通常没有进行疼痛管理.
- 在此过程中,有关镇静和镇痛的做法存在差异.
研究的目的:
- 为了确定阿片类药物止痛和镇静在小耳内减少期间的患病率.
- 评估镇痛/镇静与肠道穿孔之间的关联.
- 为了评估止痛/镇静和减轻成功之间的关系.
主要方法:
- 来自14个国家的86个机构的医疗记录的横截面研究.
- 包括3203名年龄在4-48个月的儿童,他们接受了大眼内缩减术.
- 分析了关于阿片类药物使用,镇静,穿孔和减少成功的数据.
主要成果:
- 超过三分之二的患者没有接受止痛或镇静.
- 阿片类药物的使用率为12.6%,镇静剂为10.6%,两者均为5.7%.
- 无论是镇痛还是镇静都与肠道穿孔或在调整后的分析中未能减少显著相关.
结论:
- 这项研究挑战了针对小儿内减轻疼痛缓解和镇静的常规禁用.
- 调查结果表明,目前的做法可能没有证据支持安全性和有效性.
- 进一步的研究可能会为在此过程中对疼痛管理的更新指南提供信息.
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