了解食品加工厂中发现的不同表面和环境生物膜如何影响COVID-19的传播
Austin Featherstone1, Amanda Claire Brown1, Sapna Chitlapilly Dass1
1Department of Animal Science, Texas A&M University, College Station, Texas, United States of America.
PloS one
|June 7, 2023
概括
肉类植物中的生物膜可能藏和散布SARS-CoV-2,造成健康风险. 虽然生物膜减少了传染性病毒,但它们可能会防止消毒剂,增加病毒流行潜力.
科学领域:
- 环境微生物学环境微生物学
- 病毒学 病毒学
- 食品安全科学 食品安全科学
背景情况:
- 肉类加工厂是SARS-CoV-2爆发的高风险环境.
- 生物膜是病原体持久性和传播的潜在储库.
- 了解病毒-生物膜相互作用对于食品设施的感染控制至关重要.
研究的目的:
- 研究生物膜在肉类加工环境中保护和分散冠状病毒的作用.
- 评估在常见的食品加工表面上的生物膜中冠状病毒替代品的生存能力和检测能力.
- 探索环境生物膜和病毒之间的相互作用.
主要方法:
- 在不钢,PVC和陶上使用肉类加工设施排水样本开发混合物种生物膜.
- 用小鼠肝炎病毒 (MHV) 作为SARS-CoV-2代用物对生物膜进行注射.
- 定量PCR和斑块分析以确定病毒活力和数量在7°C的潜伏后.
主要成果:
- 小鼠肝炎病毒 (MHV) 在所有测试表面的生物膜中保持活力和可检测.
- 与没有生物膜的表面相比,生物膜显著减少了传染性病毒斑块数量.
- 病毒生物膜生物量增加了两倍,这表明细菌对病毒的反应.
结论:
- 环境生物膜可以容纳并潜在地保护冠状病毒,包括SARS-CoV-2,免受肉类加工厂的消毒.
- 病毒和生物膜之间存在复杂的相互作用,影响病毒的生存和分散.
- 这些发现强调了需要有效的生物膜控制策略,以减轻病毒传播并确保食品安全.
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