儿科呼吸道同胞性病毒诊断测试性能:系统性审查和元分析
Chukwuemeka Onwuchekwa1, Jessica Atwell2, Laura Mora Moreo1
1P95 Epidemiology and Pharmacovigilance, Leuven, Belgium.
The Journal of infectious diseases
|June 7, 2023
概括
在儿童的测试中添加更多的呼吸道同胞性病毒 (RSV) 样品类型并没有显著增加检测. 然而,即使病例检测的小幅增加也可能影响儿科RSV的负担估计.
科学领域:
- 儿童传染病 儿童传染病
- 诊断微生物学 诊断微生物学
- 流行病学 流行病学
背景情况:
- 在儿童中,呼吸道同胞性病毒 (RSV) 诊断通常依赖于鼻口腔拭子 (NPS) 逆转录聚合酶链反应 (RT-PCR).
- 以前在成年人身上进行的研究表明,添加样本类型可以改善RSV检测.
- 额外的样本类型对儿科RSV检测和诊断不足的影响尚未得到充分量化.
结论:
- 对于儿科RSV,RT-PCR仍然是最敏感的诊断测试.
- 虽然增加多个标本并没有大幅增加检测率,但对疾病负担估计的累积影响需要进一步评估.
- 优化诊断策略对于准确的儿科RSV监测至关重要.
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