通过可控固定离子液体到Poly (乳酸) 链上的工程和耐用的抗微生物聚合物
Qingsong Wu1, Wentao Luo1, Yanqiu Du1,2
1College of Materials and Textile Engineering, Jiaxing University, Jiaxing 314001, China.
Biomacromolecules
|June 7, 2023
概括
使用电子束辐射将离子液体移植到聚乳酸 (PLA) 上,从而产生抗菌性PLA材料. 这些修改后的PLA无布显示出改善的稳定性和耐久的抗菌活性,用于医疗和包装应用.
科学领域:
- 材料科学 材料科学 材料科学
- 聚合物化学 聚合物化学
- 生物医学工程 生物医学工程
背景情况:
- 聚乳酸 (PLA) 广泛用于医疗应用.
- 开发有效的抗微生物PLA材料具有显著的兴趣.
- 修改PLA的方法对于增强其性能至关重要.
研究的目的:
- 为了提高性能,将离子液体 (IL) 植入PLA链上.
- 为了研究在电子束 (EB) 辐射下PLA/IL混合物的混合性和稳定性.
- 探索改性PLA在抗菌应用中的潜力.
主要方法:
- 使用EB辐射将1 - 乙烯 - 3 - - 乙利米达二 (trifluoromethylsulfonyl) 胺接种到PLA上.
- PLA-g-IL共聚合物的特征及其特性.
- 电PLA-g-IL共聚合物形成纳米纤维.
- 对抗微生物活性和耐久性的评估.
主要成果:
- 将IL成功移植到PLA链上,改善EB辐射下的混合性和化学稳定性.
- PLA-g-IL共聚合物表现出优异的电成型特性.
- 纳米纤维上的螺旋结构被消除了0.5%的ILs,增强了离子导电性.
- PLA-g-IL无布表现出了卓越而持久的抗菌活性.
结论:
- 电子束辐射提供了一种可行的方法,用于在低剂量下用功能ILs修改PLA.
- 开发的PLA-g-IL无布对于医疗和包装行业具有重大潜力.
- 这种方法为创造先进的抗微生物材料提供了一个有前途的战略.
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