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Updated: Jul 27, 2025

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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Nucleoside Triphosphates - From Synthesis to Biochemical Characterization

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序列特定的双重DNA结合模式和N-6功能化的诺克里普托塔基因类化合物的细胞毒性

Bhim Majhi1,2, Sudakshina Ganguly3, Subhadeep Palit1

  • 1Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Kolkata 700032, India.

Journal of natural products
|June 7, 2023
PubMed
概括

修改一种印罗基诺林类化物诺克里普托塔基因,降低了其DNA结合和细胞毒性. 通过改变DNA相互作用机制,N-6替代类型显示出治疗开发的潜力.

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