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产后出血和产后抑郁症:观察性研究的系统审查和元分析

Georgios Schoretsanitis^1,2,3, Chiara Gastaldon^4,5, Nicole Ochsenbein-Koelble^6,7

¹Department of Psychiatry, Psychotherapy and Psychosomatics, Hospital of Psychiatry, University of Zurich, Zurich, Switzerland.

Acta psychiatrica Scandinavica

|June 7, 2023

概括

经历产后出血 (PPH) 的妇女面临更高的产后抑郁症 (PPD) 风险. 在那些有抑郁或焦虑史的人群中,这种风险会增加,这凸显了有针对性的支持的必要性.

科学领域:

产科和妇科产科和妇科
围产期心理健康围产期心理健康
流行病学流行病学

背景情况:

产后出血 (PPH) 是一个重要的产科并发症.
产后抑郁症 (PPD) 影响了全球相当数量的女性.
PPH和PPD之间的关联需要进一步调查,特别是在缓和因素方面.

研究的目的:

为了评估产后抑郁症 (PPD) 在经历过产后出血 (PPH) 的妇女中的风险.
确定影响PPH和PPD之间的关系的潜在调节者.
通过对观察性研究的元分析来综合现有证据.

主要方法:

在Embase,Medline,PsychInfo和Cinhail数据库中进行了系统的文献搜索.
包括观察性研究,比较PPH和没有PPH的女性的PPD发病率.
超回归和子组分析检查了诸如精神健康状况的历史和国家收入水平等因素.

主要成果:

患有PPH的女性对PPD的几率比率 (OR) 增加 (1.28,95% CI 1.13-1.44).
与PPH相关的PPD风险在有抑郁/焦虑史的女性 (OR 1.37) 和低收入/中等收入国家 (OR 1.49) 中较高.
排除低质量的研究减少了整体PPD几率比率 (1.14,95% CI 1.02-1.29)).

结论:

产后出血与产后抑郁症的风险显著增加有关.
患有抑郁症或焦虑症的病史加剧了PPH后的PPD风险.
需要从低收入和中等收入国家进行进一步的研究,以充分理解PPH-PPD关联.

关键词:

抗抑郁药是一种抗抑郁药.情绪障碍情绪障碍情绪障碍围产期心理健康围产期心理健康产后抑郁症产后抑郁症产后出血产后出血是什么

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