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设计的α-sheet会破坏尿病原菌大肠杆菌生物膜,使细菌对抗生素和免疫细胞敏感

Alissa Bleem1, Tatum Prosswimmer2, Ruying Chen1,3

  • 1Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.

Scientific reports
|June 7, 2023
PubMed
概括

这项研究揭示了针对α-sheet结构的合成可以抑制尿病原性大肠杆菌生物膜中的curli amyloid纤维的形成,为抗击感染提供了一种新的非抗生素方法.

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