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Updated: Jul 27, 2025

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分子动力学模拟揭示了RhoGDI1对Cdc42的抑制机制

Yijing Zhang1, Shiyao Chen1, Taeyoung Choi1

  • 1School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China.

Journal of computer-aided molecular design
|June 7, 2023
PubMed
概括

在非活性状态下,Rho GDP 分离抑制剂1 (RhoGDI1) 稳定细胞分裂控制蛋白42同位素 (Cdc42). 分子动力学模拟显示,RhoGDI1保持Cdc42开关区域的闭合形状,为癌症治疗提供了洞察力.

关键词:
Cdc42 在线播放国内生产总值 (GDP) 分离.模拟MDMD的模拟这就是RhoGDI1DI.

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