在动脉再血管化中测量热素的价值:一个范围审查
Ksenija Jovanovic1,2, Ranko Trailovic1,2, Magnus Jonsson3,4
1Center for Anesthesiology and Resuscitation, University Clinical Center of Serbia, Belgrade, Serbia.
概括
在手术前对托波宁的测量可以帮助预测心血管内关节切除术 (CEA) 或支架 (CAS) 后的心脏并发症. 高水平的托波因与心肌梗塞风险增加,主要心脏不良事件和这些患者的死亡率有关.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 神经外科 神经外科
背景情况:
- 经过心动脉内关节切除术 (CEA) 或心动脉支架 (CAS) 的患者面临心脏并发症的重大风险.
- 在经过CEA/CAS后预测这些事件时,经外科手术时使用的热血素的有用性仍然不完全理解.
研究的目的:
- 系统地审查现有证据,以预测CEA/CAS患者心脏事件的外科手术期间热血素的预测值.
- 识别知识缺口并指导该领域的未来研究.
主要方法:
- 在MEDLINE和Web of Science上进行了系统的文献搜索,搜索到2022年3月15日之前以英语出版的研究.
- 包括的研究重点是外科手术期间的类素,心肌损伤,心肌梗塞 (MI),主要心脏不良事件 (MACE) 和CEA/CAS患者的死亡率.
- 研究选择和数据提取由多个独立审稿人进行.
主要成果:
- 包括四项涉及885名参与者的研究.
- 热素升高的危险因素 (1115.3%) 包括年龄,慢性脏病,冠状动脉疾病和心力衰竭.
- 术后热素升高与心脏病发作率 (23.540%),MACE (26.5%) 和长期死亡率的增加显著相关.
结论:
- 在经历CEA/CAS的患者中,对预测心脏不良事件有价值.
- 需要进一步的研究来澄清手术前热素的作用,最佳的采样策略和不同手术技术的比较.
- 这一评论为临床医生提供了关键的见解,并可能为减少心脏并发症的实践变化提供信息.
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