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Updated: Jul 27, 2025

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation
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在反转重复DNA上的法尔内索伊德X受体/视网状X受体异构体的结构基础

Longying Jiang1, Xueke Liu1, Xujun Liang1

  • 1Department of Pathology, NHC Key Laboratory of Cancer Proteomics, State Local Joint Engineering Laboratory for Anticancer Drugs, Department of Oncology, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Computational and structural biotechnology journal
|June 8, 2023
PubMed
概括

法尔内索伊德X受体 (FXR) 与视网膜X受体 (RXR) 形成异构体,以调节基因表达. 这项研究阐明了FXR/RXR复合物如何结合DNA,揭示了IR1位点的独特相互作用.

关键词:
晶体结构 晶体结构法尔内索伊德X受体的受体这是一种异构聚合物 (heterodimer).反向重复DNA的反向重复DNA视网膜X受体的受体X受体

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