职业作为性别角色和系统性硬化症的结果
Fatema Alkhamees1, Oriana Hoi Yun Yu1,2, Mianbo Wang2
1Jewish General Hospital, McGill University, Montreal, QC, Canada.
Journal of scleroderma and related disorders
|June 8, 2023
概括
这项研究发现,反映性别角色的职业分数与系统性硬化症结果之间没有联系. 需要对经过验证的性别措施进行进一步的研究,以了解性别性别.
科学领域:
- 风湿病学和免疫学
- 社会医学科学 社会医学科学
- 职业健康 职业健康 职业健康
背景情况:
- 在全身性硬化症 (SSc) 发病和进展方面,性别差异得到了认可.
- 有限的数据存在于性别的影响,不同于生物性别,在SSc.
- 探讨了职业作为性别相关角色及其对SSc的影响的代理.
研究的目的:
- 调查职业分数与SSc结果之间的关联.
- 为了确定职业是否作为与性别相关的因素,可以独立预测SSc疾病特征和患者体验.
主要方法:
- 根据2016年国家职业分类制定了一项职业分数,区分男性和女性主导的职业.
- 来自加拿大硬化皮肤病研究小组注册表的1104名SSc患者被根据自我报告的职业分配了分数.
- 根据性别,年龄,吸烟和教育情况调整的多变量模型分析了职业得分对SSc结果的影响.
主要成果:
- 在性别之间观察到疾病持续时间,扩散性疾病患病率,间歇性肺病和肺高血压的显著差异.
- 女性和男性的中位数职业分数显著不同,性别和职业分数之间的相关性较弱.
- 经过调整后的分析显示,职业得分对SSc子集,间歇性肺病,肺高血压,疼痛,治疗反应或死亡率没有独立的预测效应.
结论:
- 在职业分数 (作为性别的代理) 和系统性硬化症结果之间没有发现独立的关联.
- 职业可能是性别的不充分衡量标准,因此在解释这些发现时需要谨慎.
- 未来的研究需要经过验证的性别措施,以有力地评估性别在全身性硬化症中的作用.
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