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Updated: Jul 27, 2025

Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells
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Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells

Published on: July 6, 2021

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针对KRAS的目标

Qi Ai1,2,3, Fanlu Li1,2,3, Siyi Zou1,2,3

  • 1Department of General Surgery, Pancreatic Disease Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Frontiers in immunology
|June 8, 2023
PubMed
概括

KRASG12V新抗原特异性T细胞受体 (TCR) 工程T细胞显示出治疗固体瘤的前景. 这项研究确定了一种针对CD4+T细胞中的KRASG12V的新型TCR,在中国人群中有效.

关键词:
在KRAS G12V突变中.工程T细胞受体-工程T细胞受体-T细胞人类白细胞抗原-DPB*0301人类白细胞抗原DPB*1401免疫疗法 免疫疗法固体瘤是一个固体瘤.

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