乳房扫描对怀疑 (乳房成像报告和数据系统IV) 乳房病变的患者的应用
Ali Reza Azarpeikan1, Ramesh Omranipour1, Habibollah Mahmoodzadeh2
1Department of Surgical Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Advanced biomedical research
|June 8, 2023
概括
乳房扫描可以帮助确定哪些乳房成像报告和数据系统 (BIRADS) 的IV病变需要手术. 吸收阳性病变需要手术,而吸收阴性病例需要进一步评估.
科学领域:
- 核医学是一种核医学.
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 乳腺成像报告和数据系统 (BIRADS) 的IV病变手术需要支持成像或病理学数据.
- 在这种情况下,乳房光学扫描的实用性仍然不清楚.
研究的目的:
- 评价乳房扫描在手术前评估BIRADS IV病变中的作用.
- 为了确定乳腺扫描在区分良性和恶性BIRADS IV病变的诊断准确性.
主要方法:
- 一项前性研究,包括16名患有25个BIRADS IV病变的患者,计划进行手术.
- 使用非专用玛摄像头进行的乳房光学扫描,用99mTc-MIBI注射在倾斜位置进行.
- 在15分钟和60分钟内分析瘤与非瘤吸收率 (T/NT),包括单光子发射计算断层扫描 (SPECT) 投影.
主要成果:
- 在25个病变中,12个是恶性的,13个是良性的.
- 在15分钟后,恶性病变呈现出更高T/NT比率的趋势 (22.8±23.9对10.1±10.1;P=0.109).
- 20的最佳T/NT截止值为7.7%的良性病变虚假阳性率,整体诊断准确度,灵敏度和特异性分别为0.68,0.42和0.92.
结论:
- 用SPECT成像进行乳房扫描可能有助于选择BIRADS IV病变进行手术.
- 剪影仪的积极吸收表明需要进行手术干预.
- 吸收阴性病例需要根据额外的临床和成像数据做出决定.
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