水性和水性酒精提取物的改善作用
Mohsen Minaiyan1, Parastoo Pasandideh-Fetrat2, Masoud Sadeghi-Dinani3
1Department of Pharmacology, School of Pharmacy and Pharmaceutical Sciences Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran.
Advanced biomedical research
|June 8, 2023
概括
斯克罗普鲁拉里亚条纹菌提取物在治疗性结肠炎方面表现有前途. 液醇提取物 (SSHE) 在大鼠模型中显示出显著的抗炎和抗氧化作用,这表明它有可能成为一种新的草药疗法.
科学领域:
- 药理学 药理学是指药理学的学科.
- 植物化学 植物化学
- 胃肠病学 胃肠病学
背景情况:
- 斑马 (S. striata) 具有抗炎,抗氧化,抗微生物和伤口愈合的特性.
- 传统的炎症性肠病 (IBD) 治疗有相关的副作用.
- 研究S.striata提取物作为潜在的替代性治疗大肠炎.
研究的目的:
- 评估S. striata的水性 (SSAE) 和水性酒精 (SSHE) 提取物的抗结肠炎特性.
- 在小鼠实验性结肠炎模型中评估S.striata提取物的疗效.
主要方法:
- 大肠炎被诱导在老鼠使用乙酸.
- 鼠被用不同剂量的SSAE或SSHE,德克萨米他或梅萨拉治疗.
- 测量的主要参数包括结肠体重/身高,指数,大肠炎总指数,骨髓氧化酶 (MPO) 和马隆迪 (MDA) 水平.
主要成果:
- SSHE和最高剂量的SSAE显著降低了大肠炎的宏观和病理指数,以及MPO和MDA水平.
- 与SSAE相比,SSHE的总含量较高.
- 较低剂量的SSAE在减少大肠炎特征和生化标志物方面效果较差.
结论:
- S. striata,特别是SSHE,对性结肠炎有有益影响.
- 植物的治疗作用很可能是由其抗氧化,抗炎和伤口愈合的特性介导的.
- 需要进一步的研究来确定S.striata作为一种可行的大肠炎的草药治疗方法.
关键词:
抗炎药物是一种抗炎药物.斯克罗普鲁拉里亚菌是什么?大肠炎是一种大肠炎.植物提取物植物提取物鼠类 鼠类 鼠类 鼠类 鼠类条纹条纹 (striata striata) 是一个的发作 的发作 的发作更多相关视频
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