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Updated: Jul 27, 2025

Fluorescence Biomembrane Force Probe: Concurrent Quantitation of Receptor-ligand Kinetics and Binding-induced Intracellular Signaling on a Single Cell
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多复合单分子力谱法用于剖析活细胞上膜受体功能的生物物理调节

Chenyi An1, Wei Chen1,2,3

  • 1Department of Cell Biology and Department of Cardiology of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310058, China.

Biophysics reports
|June 8, 2023
PubMed
概括

本综述强调了先进的活细胞单分子力光谱 (SMFS) 用于研究膜受体. 新技术提供了增强的机械稳定性和成像,以探索复杂的生物物理调节.

关键词:
生物物理调节 生物物理调节活细胞是活细胞.膜受体受体是什么 膜受体受体受体多重复合 SMFS 技术

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Protein Dynamics in Living Cells01:19

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Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...
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